The Future of Clinical Trials: Expertise in Decentralized Clinical Trials (DCTs)
The clinical trial landscape is undergoing a fundamental transformation. Decentralized Clinical Trials (DCTs) – once considered an experimental approach – have rapidly evolved into an essential component of the modern research ecosystem. This shift is creating unprecedented demand for professionals with specialized skill sets who can navigate the intersection of clinical research, digital technology, and patient engagement.
The Evolution of Decentralized Trials
Decentralized Clinical Trials leverage digital technologies to conduct some or all trial activities outside traditional research sites. While the COVID-19 pandemic accelerated their adoption out of necessity, forward-thinking organizations are now embracing DCTs as a permanent, strategic approach to clinical research.
"Spurred in part by the ongoing COVID-19 pandemic, DCTs are bringing more technology to clinical research and along with it the promise of greater efficiency, productivity, and effectiveness," notes Jim Kremidas, Executive Director of the Association of Clinical Research Professionals (ACRP). "But to fully realize that potential, roles will need to evolve and operate differently to accommodate this new environment."[^1]
The U.S. Food and Drug Administration (FDA) has recognized the potential of DCTs to enhance trial accessibility and participant diversity. These approaches, when combined with digital health technologies, can capture data more frequently – sometimes continuously – while providing insights into how treatments perform in real-world settings.[^2]
Emerging Talent Needs in Decentralized Trials
The expansion of DCTs is creating entirely new career paths while transforming traditional clinical research roles. Organizations seeking to implement successful decentralized or hybrid trials need professionals with expertise in several key areas:
Technical Proficiency
- Experience with remote monitoring platforms and telehealth systems
- Understanding of digital health technologies and wearable devices
- Data security and privacy expertise specific to healthcare applications
Patient Engagement
- Skills in virtual recruitment and retention strategies
- Experience designing user-friendly participant interfaces
- Ability to provide remote support and troubleshooting for participants
Regulatory Navigation
- Knowledge of evolving regulatory frameworks for DCTs
- Understanding of data integrity requirements in virtual environments
- Experience with electronic consent processes and documentation
New and Evolving Roles in the DCT Ecosystem
The ACRP has identified several emerging positions that are becoming critical to decentralized trial success:[^1]
Remote Trial Coordinator
This evolving role adapts traditional coordinator responsibilities to the virtual environment. Remote coordinators manage participant interactions across digital platforms, ensuring protocol compliance and data quality without in-person visits.
Virtual Patient Guide
These specialists focus exclusively on the participant experience, providing technical support, answering questions, and maintaining engagement throughout the trial journey.
Decentralized Investigator
Clinical investigators in DCT settings must develop new skills to effectively oversee research conducted remotely, adapting their oversight and assessment processes to virtual environments.
Tech Trainer and Site Tech Support
These specialized roles ensure that both site staff and participants understand how to use the digital tools involved in decentralized trials, providing ongoing support to minimize technical barriers.
Importantly, the majority of near-term trials will likely be hybrid models rather than fully decentralized, creating demand for professionals who can navigate both traditional and virtual trial environments seamlessly.[^1]
Operational Challenges and Talent Solutions
Despite their benefits, decentralized trials present significant implementation challenges. BioSpace identifies several key hurdles, including complex stakeholder ecosystems and significant skills gaps. Organizations must address these challenges through strategic workforce development, including reskilling, upskilling, and a focused emphasis on digital competencies.[^3]
Successful DCT implementation requires not just acquiring new talent but developing existing team members. Technology training must become standard practice, written into site manuals and delegation logs to ensure all staff can effectively leverage digital tools.[^1]
Diversity and Inclusion Imperatives
Beyond operational considerations, decentralized trials offer significant potential to address historical inequities in clinical research. The ability to participate remotely can reduce barriers for underrepresented populations, but realizing this potential requires intentional strategies and diverse leadership.
Companies like Abbott are investing in initiatives to foster diversity in clinical trials. Their $5 million scholarship program aims to support medical students from underrepresented backgrounds, addressing the historical lack of inclusion in clinical research.[^3]
"Diversity in medicine improves patient outcomes and decreases health disparities," note researchers from the Journal of the American Medical Association Surgery, highlighting the connection between diverse clinical teams and more inclusive trial participation.[^3]
Building Your DCT Talent Strategy
For organizations navigating the transition to decentralized trials, several approaches can help build world-class DCT
capabilities:
- Develop Hybrid-Skilled Teams Rather than searching exclusively for candidates with all the necessary skills, create cross-functional teams combining clinical expertise, technical proficiency, and patient engagement capabilities.
- Invest in Training and Development Upskill existing research professionals with focused training on digital technologies, remote participant management, and virtual data collection.
- Create Clear Career Pathways Develop structured career development frameworks that recognize and reward DCT expertise, encouraging professionals to specialize in this growing field.
- Partner with Specialized Recruiters Work with talent acquisition partners who understand the unique requirements of decentralized trials and can access specialized candidate pools.
The Path Forward
As decentralized trials continue to reshape the clinical research landscape, organizations that build robust DCT capabilities will gain a significant competitive advantage. By developing talent strategies that address the unique skill requirements of virtual and hybrid trials, research sponsors can enhance efficiency, accelerate recruitment, and ultimately bring innovative treatments to patients more quickly.
For those navigating this transformation, partnering with recruitment specialists who understand the evolving talent landscape can provide critical support in building teams equipped for the future of clinical research.
To discuss your organization's DCT talent needs, contact The Pharma:Health Practice today.
Footnotes
- "Rise of Technology, Decentralized Clinical Trials Requires Unprecedented Transformation of Clinical Trial Workforce," Association of Clinical Research Professionals, August 2020.
- "The Evolving Role of Decentralized Clinical Trials and Digital Health Technologies," U.S. Food and Drug Administration, May 2023.
- "Decentralized Clinical Trials Are the Future; Here's How to Avoid Pitfalls," BioSpace, January 2024.








